RARECHEM EM WB 0198

RARECHEM EM WB 0198 - Names and Identifiers

Name	1-[1-(tert-butoxycarbonyl)piperidin-4-yl]-L-proline
Synonyms	RARECHEM EM WB 0198 L-N-[(4-BOC)PIPERIDINO]PROLINE L-N-[(4'-Boc)piperidino]proline L-N-[(4'-BOC)PIPERIDINO]PROLINE N-(1-BOC-PIPERIDIN-4-YL)-L-PROLINE 1-[1-(tert-butoxycarbonyl)piperidin-4-yl]-L-proline 1-[1-(tert-Butoxycarbonyl)piperidin-4-yl]-L-proline (S)-1-(1-N-BOC-PIPERIDIN-4-YL) PYRROLIDINE-2-CARBOXYLIC ACID (S)-1-(1-(TERT-BUTOXYCARBONYL)PIPERIDIN-4-YL)PYRROLIDINE-2-CARBOXYLIC ACID (S)-4-(2-CARBOXY-PYRROLIDIN-1-YL)-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 4-[(2S)-2-Carboxy-1-pyrrolidinyl]-1-piperidinecarboxylic acid 1-tert-butyl ester 1-Piperidinecarboxylic acid, 4-[(2S)-2-carboxy-1-pyrrolidinyl]-, 1-(1,1-dimethylethyl) ester
CAS	221352-39-2
InChI	InChI=1/C15H26N2O4/c1-15(2,3)21-14(20)16-9-6-11(7-10-16)17-8-4-5-12(17)13(18)19/h11-12H,4-10H2,1-3H3,(H,18,19)/t12-/m0/s1

RARECHEM EM WB 0198 - Physico-chemical Properties

Molecular Formula	C15H26N2O4
Molar Mass	298.38
Density	1.191±0.06 g/cm3(Predicted)
Boling Point	427.9±45.0 °C(Predicted)
Flash Point	212.6°C
Vapor Presure	1.6E-08mmHg at 25°C
pKa	2.29±0.20(Predicted)
Storage Condition	Sealed in dry,2-8°C
Refractive Index	1.532

RARECHEM EM WB 0198 - Risk and Safety

Hazard Symbols	N - Dangerous for the environment
Risk Codes	50 - Very Toxic to aquatic organisms
Safety Description	61 - Avoid release to the environment. Refer to special instructions / safety data sheets.
HS Code	29333990
Hazard Class	IRRITANT

RARECHEM EM WB 0198 - Introduction

1-[1-(tert-butoxycarbonyl)piperidin-4-yl]-L-proline is an organic compound with the formula C15H25N3O4.

Properties: 1-[1-(tert-butoxycarbonyl)piperidin-4-yl]-L-proline is a solid powder, colorless to white, with a special amino acid structure, soluble in some organic solvents such as methanol and ethyl acetate.

Uses: 1-[1-(tert-butoxycarbonyl)piperidin-4-yl]-L-proline are commonly used in the field of organic synthesis, especially in peptide synthesis. It can be used as a protecting group for protecting natural amino acids or amino acids in synthetic polypeptides. In addition, it can be used to study protein structure and function, as well as in areas such as drug design and discovery.

Production Method: The preparation of 1-[1-(tert-butoxycarbonyl)piperidin-4-yl]-L-proline is usually carried out by a chemical synthesis method. A common method is the reaction of 1-proline with piperidin-4-amine and tert-butoxycarbonylchloromethane to yield 1-[1-(tert-butoxycarbonyl)piperidin-4-yl]-L-proline.

Safety information: 1-[1-(tert-butoxycarbonyl)piperidin-4-yl]-L-proline has low toxicity under general operating conditions. However, as chemicals, it is still necessary to pay attention to safe handling and avoid inhalation, contact with skin or entering the digestive system. Appropriate protective measures, such as lab gloves and goggles, should be worn during use. In case of contact with skin or eyes, rinse immediately with plenty of water. Seek medical help if necessary. During storage, it should be kept in a dry, cool place and avoid contact with oxidants and strong acids.

Last Update：2024-04-09 20:45:29